Acquired Cystic Disease-Associated Renal Cell Carcinoma
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A renal tumor with variable morphological patterns arising exclusively in end-stage kidneys with acquired cystic disease.
These tumors occur most often, but not always, in patients undergoing long-term hemodialysis with acquired cystic disease and are usually incidental finding detected during their follow-up. Often they are multiple and bilateral. It represents roughly one third of all renal cell neoplasms arising in end-stage renal disease.
365体育网站It frequently occurs in patients receiving hemodialysis of more than 10 years
There is no gender predilection.
365体育网站There is no site predilection.
Surgical treatment is recommended.
365体育网站Because of early detection of tumors in patients on periodical follow-up imaging analyses for chronic renal failure, the clinical behavior is usually indolent.
References and Further Reading
- Cossu-Rocca, P., Eble, J. N., Zhang, S., Martignoni, G., Brunelli, M., & Cheng, L. (2006). Acquired cystic disease-associated renal tumors: An immunohistochemical and fluorescence in situ hybridization study. Modern Pathology, 19, 780–787.
- Kuroda, N., Tamura, M., Hamaguchi, N., Mikami, S., Pan, C. C., Brunelli, M., Martignoni, G., Hes, O., Michal, M., & Lee, G. H. (2011). Acquired cystic disease–associated renal cell carcinoma with sarcomatoid change and rhabdoid features. Annals of Diagnostic Pathology, 15(6), 462–466.
- Pan, C. C., Chen, Y. J., Chang, L. C., Chang, Y. H., & Ho, D. M. (2009). Immunohistochemical and molecular genetic profiling of acquired cystic disease-associated renal cell carcinoma. Histopathology, 55, 145–153.
- Tickoo, S. K., deParalta-Venturia, M. N., Harik, L. R., Worcester, H. D., Salama, M. E., Young, A. N., Moch, H., & Amin, M. B. (2006). Spectrum of epithelial neoplasms in end-stage renal disease: An experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. The American Journal of Surgical Pathology, 30(2), 141–153.